Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665339 | 0.88 | BLM (0.53) | BLMLMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL27665263 | 0.86 | PRCP (0.45) | BLMLMNADPP4DPP7CYP1A2 | |
| SCHEMBL27665715 | 0.86 | MME (0.41) | BLMDPP4DPP8DPP7CYP1A2 | |
| SCHEMBL27644323 | 0.84 | KDM4E (0.39) | BLMCYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL28761408 | 0.84 | ACHE (0.47) | BLMACHEALOX5LMNACYP1A2 | |
| SCHEMBL27644015 | 0.84 | BLM (0.36) | BLMLMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL27665405 | 0.84 | DPP4 (0.43) | DPP4DPP8DPP7CNR2CYP2D6 | |
| SCHEMBL27665619 | 0.82 | ACP3 (0.39) | BLMCYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL27644024 | 0.81 | TDP1 (0.52) | BLMLMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL28758277 | 0.80 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |