Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828638 | 0.82 | CYP3A4 (0.58) | CYP3A4SLC7A5 | |
| SCHEMBL29593008 | 0.82 | CYP3A4 (0.54) | CYP3A4SLC7A5 | |
| SCHEMBL27806348 | 0.82 | CYP3A4 (0.60) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL24725104 | 0.82 | CYP3A4 (0.53) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL29728766 | 0.82 | CYP3A4 (0.60) | CYP3A4SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL27624718 | 0.79 | REN (0.51) | ERAP2ERAP1LNPEP | |
| SCHEMBL16350346 | 0.79 | REN (0.49) | ERAP2ERAP1LNPEP | |
| SCHEMBL12972224 | 0.79 | REN (0.49) | ERAP2ERAP1LNPEP | |
| SCHEMBL12232397 | 0.78 | REN (0.48) | ERAP2ERAP1LNPEP | |
| SCHEMBL18402423 | 0.77 | REN (0.60) | ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100534535-C | Improved linkers for pharmaceutical compounds | BRACCO IMAGING SPA (IT) | 2009-09-02 | — | — | CN | disclosed |
| CN-1738652-A | Improved linkers for pharmaceutical compounds | BRACCO IMAGING SPA (IT) | 2006-02-22 | — | — | CN | disclosed |