Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PMM2 | O15305 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568249 | 0.86 | GAA (0.56) | GAAGRM2ALDH1A1LMNAMAPK1 | |
| SCHEMBL8568619 | 0.80 | ROCK2 (0.56) | GAAKMT2AMAPT | |
| SCHEMBL8568624 | 0.80 | ROCK2 (0.56) | GAAKMT2AMAPT | |
| SCHEMBL18048721 | 0.79 | KMT2A (0.45) | ALDH1A1LMNAMAPK1TP53HPGD | |
| SCHEMBL6566908 | 0.78 | GAA (0.48) | GAAGRM2ALDH1A1LMNAMAPK1 | |
| SCHEMBL7421223 | 0.77 | GAA (0.47) | GAAGRM2ALDH1A1LMNAMAPK1 | |
| SCHEMBL30443816 | 0.76 | KDM1A (0.54) | GAAGRM2ALDH1A1LMNAMAPK1 | |
| SCHEMBL4121023 | 0.76 | GAA (0.57) | GAAGRM2ALDH1A1LMNAMAPK1 | |
| SCHEMBL5853439 | 0.76 | KDM1A (0.54) | GAAGRM2ALDH1A1LMNAMAPK1 | |
| SCHEMBL132460 | 0.75 | GAA (0.55) | GAAGRM2ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591317-A | P2X3 inhibitors and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-06-07 | — | — | CN | disclosed |