Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.63 |
| ▸ | GLS | O94925 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629418 | 0.86 | RAB9A (0.68) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL27571956 | 0.85 | ATM (0.63) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL5629412 | 0.85 | ATM (0.63) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL14192408 | 0.85 | KAT8 (0.69) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL12002438 | 0.82 | SMN1; SMN2 (0.69) | GAAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8832776 | 0.82 | KAT8 (0.74) | GAAMAPTALDH1A1SMN1; SMN2KAT8 | |
| SCHEMBL8282186 | 0.82 | KAT8 (0.65) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL12354953 | 0.82 | KAT8 (0.65) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL8308646 | 0.80 | GAA (0.60) | ATMGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL6374705 | 0.80 | RAB9A (0.69) | ATMGAAMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1849302-A | 1, 3-disubstituted azetidine derivatives useful as CCR-3 receptor antagonists in the treatment of inflammatory and allergic diseases | NOVARTIS AG (CH) | 2006-10-18 | — | — | CN | disclosed |