Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | GLS | O94925 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192408 | 0.86 | KAT8 (0.69) | KAT8POLBCYP1A2ALDH1A1GAA | |
| SCHEMBL12354953 | 0.83 | KAT8 (0.65) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL8282186 | 0.83 | KAT8 (0.65) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL28759581 | 0.82 | ATM (0.67) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL29360795 | 0.81 | KAT8 (0.58) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL11509330 | 0.81 | SMN1; SMN2 (0.81) | HSD17B10POLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5629418 | 0.80 | RAB9A (0.68) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL29353446 | 0.80 | KAT8 (0.61) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL6374673 | 0.79 | KAT8 (0.60) | KAT8HSD17B10POLBALDH1A1GAA | |
| SCHEMBL27571956 | 0.79 | ATM (0.63) | KAT8HSD17B10POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |