Piperidine

Piperidine

SCHEMBL28759890

C1CCNCC1.O=C(c1ccccc1)c1ccc(F)cc1[N+](=O)[O-]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
CES2 O00748 1/20 0.43
MAPK1 P28482 2/20 0.41
VCAM1 P19320 1/20 0.41
MAPT P10636 5/20 0.41
LMNA P02545 3/20 0.41
HTT P42858 3/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KCNMA1 Q12791 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
TTR P02766 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP2C9 P11712 2/20 0.41
RECQL P46063 2/20 0.41
MEN1 O00255 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27509324 0.88 ALDH1A1 (0.56) ALDH1A1CES2MAPK1VCAM1MAPT
Piperidine SCHEMBL27676223 0.85 ALDH1A1 (0.49) ALDH1A1CES2MAPK1VCAM1MAPT
Piperidine SCHEMBL27676244 0.85 HPGD (0.49) ALDH1A1CES2MAPK1VCAM1MAPT
Piperidine SCHEMBL27656298 0.84 ALDH1A1 (0.49) ALDH1A1MAPK1VCAM1MAPTLMNA
SCHEMBL27729180 0.82 ALDH1A1 (0.50) ALDH1A1CES2MAPK1VCAM1MAPT
Piperazine SCHEMBL28754151 0.78 HPD (0.51) ALDH1A1CES2MAPK1MAPTLMNA
SCHEMBL27540677 0.77 ALDH1A1 (0.56) ALDH1A1CES2MAPK1VCAM1MAPT
Piperazine SCHEMBL28142889 0.77 ALDH1A1 (0.52) ALDH1A1MAPK1VCAM1MAPTHTT
Piperazine SCHEMBL28112864 0.76 ALDH1A1 (0.51) ALDH1A1MAPK1VCAM1MAPTHTT
SCHEMBL18779475 0.73 CASP6 (0.58) ALDH1A1LMNAPOLBTTRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101837125-A The proteinic phosphorylation control method of SR and be the antiviral agent of effective ingredient with the reagent that comprises the SR protein activity regulator MASATOSHI HAGIWARA 2010-09-22 CN disclosed
CN-1921885-A Method for controlling phosphorylation of SR protein and antiviral agent comprising SR protein activity controller as active ingredient HAGIWARA MASATOSHI (JP) 2007-02-28 CN disclosed