Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299963 | 0.94 | DNMT1 (0.43) | ACP3WDR5HDAC8HDAC6GPR84 | |
| SCHEMBL28080572 | 0.82 | WDR5 (0.47) | ACP3WDR5GPR84DNMT1ALDH1A1 | |
| SCHEMBL6242989 | 0.78 | DNMT1 (0.41) | WDR5HDAC8HDAC6GPR84DNMT1 | |
| SCHEMBL29397823 | 0.76 | GPR84 (0.43) | ACP3HDAC8HDAC6GPR84DNMT1 | |
| SCHEMBL27902996 | 0.75 | ACP3 (0.46) | ACP3HDAC8HDAC6GPR84MCL1 | |
| Phosphoric Acid SCHEMBL3922368 | 0.74 | NSD2 (0.51) | ACP3GPR84DNMT1MCL1ACMSD | |
| Phosphoric Acid SCHEMBL31219446 | 0.74 | NSD2 (0.51) | ACP3GPR84DNMT1MCL1ACMSD | |
| Phosphoric Acid SCHEMBL29768762 | 0.74 | NSD2 (0.51) | ACP3GPR84DNMT1MCL1ACMSD | |
| Biphenyl SCHEMBL27770404 | 0.74 | ALDH1A1 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC8 | |
| Phosphoric Acid SCHEMBL29911372 | 0.74 | ACP3 (0.55) | ACP3HDAC8HDAC6GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823057-A | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORP (US) | 2006-08-23 | — | — | CN | disclosed |