Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435770 | 0.78 | MAPK1 (0.50) | HSD11B1MAPK1 | |
| SCHEMBL11655966 | 0.75 | MAPT (0.51) | HSD11B1TRPC5MAPTCRBNDDB1 | |
| SCHEMBL3974078 | 0.71 | HSD11B1 (0.51) | HSD11B1TRPC5LMNAESR1P2RX7 | |
| SCHEMBL378251 | 0.68 | TOP2A (0.50) | MAPTCRBNALDH1A1LMNATOP2A | |
| SCHEMBL16597500 | 0.68 | TOP2A (0.50) | MAPTCRBNALDH1A1LMNATOP2A | |
| SCHEMBL2536247 | 0.67 | DDB1 (0.72) | MAPTCRBNDDB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5597469 | 0.67 | RAB9A (0.43) | MAPTCRBNDDB1ALDH1A1LMNA | |
| SCHEMBL10765254 | 0.65 | TOP2A (0.46) | MAPTCRBNALDH1A1LMNATOP2A | |
| SCHEMBL11086765 | 0.65 | TOP2A (0.46) | MAPTCRBNALDH1A1LMNATOP2A | |
| SCHEMBL27618934 | 0.65 | TOP2A (0.46) | MAPTCRBNALDH1A1LMNATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863877-A | Be used for the treatment of the treatment of pain agent | EURO CELTIQUE SA | 2010-10-20 | — | — | CN | disclosed |
| CN-1835751-B | Therapeutic agent for treating pain | EURO CELTIQUE SA | 2010-06-23 | — | — | CN | disclosed |
| CN-1835751-A | therapeutic agent for treating pain | EURO CELTIQUE SA (LU) | 2006-09-20 | — | — | CN | disclosed |