Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388467 | 0.91 | GPR119 (0.60) | GPR119 | |
| SCHEMBL387669 | 0.91 | GPR119 (0.60) | GPR119 | |
| SCHEMBL385347 | 0.91 | GPR119 (0.60) | GPR119 | |
| SCHEMBL386671 | 0.85 | GPR119 (0.57) | GPR119 | |
| SCHEMBL2882005 | 0.82 | GPR119 (0.49) | GPR119 | |
| SCHEMBL4053560 | 0.80 | GPR119 (0.52) | GPR119 | |
| SCHEMBL384779 | 0.80 | GPR119 (0.58) | GPR119 | |
| SCHEMBL387399 | 0.78 | GPR119 (0.60) | GPR119 | |
| SCHEMBL388696 | 0.78 | GPR119 (0.60) | GPR119 | |
| SCHEMBL386557 | 0.77 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010512334-A | — | — | 2010-04-22 | — | — | JP | claimed |
| EP-2094683-A2 | BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS | SmithKline Beecham Corporation (US) | 2009-09-02 | — | — | EP | claimed |
| WO-2008070692-A2 | BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-12 | — | — | WO | claimed |