Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920011 | 0.80 | APLNR (0.40) | CA2CA1CA12CA9APLNR | |
| SCHEMBL28762094 | 0.76 | CA1 (0.44) | CA2CA1CA12CA7CA9 | |
| SCHEMBL28942736 | 0.76 | ALDH1A1 (0.49) | CA2CA1CA12CA7CA9 | |
| SCHEMBL31311149 | 0.74 | APLNR (0.42) | CA2CA1CA12CA9CA13 | |
| SCHEMBL28335342 | 0.74 | APLNR (0.42) | CA2CA1CA12CA9APLNR | |
| SCHEMBL29155761 | 0.73 | CA12 (0.37) | CA2CA1CA12CA9APLNR | |
| SCHEMBL28415525 | 0.73 | ALDH1A1 (0.54) | CA2CA1CA12CA7CA9 | |
| SCHEMBL26617619 | 0.72 | TP53 (0.44) | APLNRTP53CNR2GAAMAPT | |
| SCHEMBL28177507 | 0.72 | PARP15 (0.36) | CA2APLNRTP53TSHRALDH1A1 | |
| SCHEMBL28758470 | 0.72 | APLNR (0.45) | APLNRTP53PTGES2CNR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |