Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671341 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL29095322 | 0.83 | CA2 (0.62) | ALDH1A1TSHRGAAHPGDHTT | |
| SCHEMBL28762094 | 0.81 | CA1 (0.44) | NPSR1CA1CA2CA12CA7 | |
| SCHEMBL28942735 | 0.78 | TP53 (0.53) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL28762093 | 0.77 | TP53 (0.51) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL3361891 | 0.76 | APLNR (0.63) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL28762162 | 0.76 | CA2 (0.46) | ALDH1A1TSHRGAAHTTMAPT | |
| SCHEMBL30926483 | 0.74 | ALDH1A1 (0.49) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL18415441 | 0.73 | TAS1R3 (0.67) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL16840113 | 0.72 | HPGD (0.60) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |