SCHEMBL2876271

SCHEMBL2876271

c1ccc(CCN2CCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 1.00
SIGMAR1 Q99720 6/20 0.96
HRH3 Q9Y5N1 4/20 0.69
L3MBTL1 Q9Y468 2/20 0.67
LTA4H P09960 1/20 0.67
MBTD1 Q05BQ5 1/20 0.67
L3MBTL3 Q96JM7 1/20 0.67
HTR1A P08908 1/20 0.66
DRD2 P14416 1/20 0.66
TDP1 Q9NUW8 1/20 0.64
ACHE P22303 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL3683452 0.98 SLC6A3 (0.96) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
SCHEMBL11589061 0.98 SIGMAR1 (1.00) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
1-Phenethylpiperidine SCHEMBL917609 0.98 SIGMAR1 (1.00) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
1-Phenethylpiperidine SCHEMBL4054824 0.98 SIGMAR1 (1.00) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
Iodide SCHEMBL3691021 0.98 SLC6A3 (0.96) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
SCHEMBL11922748 0.98 SIGMAR1 (1.00) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
Hydrochloric Acid SCHEMBL28216902 0.98 SLC6A3 (0.96) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
1-Phenethylpiperidine SCHEMBL11507835 0.96 SIGMAR1 (0.96) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
1-Phenethylpiperidine SCHEMBL11404041 0.96 SIGMAR1 (0.96) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H
1-Phenethylpiperidine SCHEMBL7524827 0.96 SIGMAR1 (0.96) SLC6A3SIGMAR1HRH3L3MBTL1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119606059-A Preparation method of filter element material for enhancing tobacco smoke adsorption 奥伯风环境科技(南京)有限公司 2025-03-14 CN claimed
CN-112441888-B Pd-ReOx/CeO2Method for preparing nitrogen-containing aromatic compound by catalyzing lignin ammoniation reaction 中国科学院大连化学物理研究所 2021-10-26 CN claimed
CN-112441888-A Pd-ReOx/CeO2Method for preparing nitrogen-containing aromatic compound by catalyzing lignin ammoniation reaction 中国科学院大连化学物理研究所 2021-03-05 CN claimed
US-10836874-B2 High performance cross-linked triblock cationic functionalized polymer for electrochemical applications, methods of making and methods of using COLORADO SCHOOL OF MINES (US) 2020-11-17 US claimed
US-20190100633-A1 HIGH PERFORMANCE CROSS-LINKED TRIBLOCK CATIONIC FUNCTIONALIZED POLYMER FOR ELECTROCHEMICAL APPLICATIONS, METHODS OF MAKING AND METHODS OF USING UNIVERSITY OF MASSACHUSETTS 2019-04-04 US claimed
EP-2702041-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF Chiesi Farmaceutici S.p.A. (IT) 2014-03-05 EP claimed
US-8604015-B2 Alkaloid ester and carbamate derivatives and medicinal compositions thereof CHIESI FARMACEUTICI S.P.A. (IT) 2013-12-10 US claimed
WO-2012146515-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF CHIESI FARMACEUTICI S.P.A. (IT) 2012-11-01 WO claimed
US-20120276018-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF CHIESI FARMACEUTICI S.P.A. (IT) 2012-11-01 US claimed
US-20100168490-A1 METHOD FOR PREPARATION OF AN ALUMINOSILICATE WITH FERRIERITE STRUCTURE FROM GELS CONTAINING TETRAMETHYLAMMONIUM AND BENZYLMETHYLPYRROLIDINE, AND USES THEREOF CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2010-07-01 US claimed
EP-2133309-A1 METHOD FOR PREPARATION OF AN ALUMINOSILICATE WITH FERRIERITE STRUCTURE FROM GELS CONTAINING TETRAMETHYL AMMONIUM AND BENZYLMETHYLPYRROLIDINE, AND USES THEREOF Consejo Superior De Investigaciones Científicas (ES) 2009-12-16 EP claimed
EP-0483580-A2 1-(2-Arylethyl)-pyrrolidine MERCK PATENT GmbH (DE) 1992-05-06 EP claimed
US-4772602-A VASODILATION, HYPOTENSIVE SUNTORY LIMITED (JP) 1988-09-20 US claimed
EP-4622743-A1 SYNTHESIS OF A HIGH PURITY IZM-8 ZEOLITE OF FER FRAMEWORK TYPE IFP Energies nouvelles (FR) 2025-10-01 EP disclosed
CN-119606059-A Preparation method of filter element material for enhancing tobacco smoke adsorption 奥伯风环境科技(南京)有限公司 2025-03-14 CN disclosed
CN-119101013-A Method for synthesizing dithiocarbamic acid ester derivative 宁夏医科大学 2024-12-10 CN disclosed
WO-1996025420-A1 CHIRAL ORGANOMETALLIC COMPOUNDS ZENECA LIMITED (GB) 1996-08-22 WO disclosed
WO-1995002567-A1 CATALYTIC ASYMMETRIC REDUCTION OF TRISUBSTITUTED OLEFINS AND ENAMINES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1995-01-26 WO disclosed
US-5232978-A 1-(2-arylethyl)-pyrrolidines MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-08-03 US disclosed
EP-0483580-A2 1-(2-Arylethyl)-pyrrolidine MERCK PATENT GmbH (DE) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120276018-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF CHRM3, BCHE, CHRM1 SLC6A3 4087/4885SIGMAR1 1448/4885HRH3 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.