Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.96 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589061 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| SCHEMBL11922748 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL4054824 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL27138909 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL11404041 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL27451069 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL11507835 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL7524827 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL31229056 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 | |
| 1-Phenethylpiperidine SCHEMBL27449208 | 0.98 | SIGMAR1 (0.96) | SIGMAR1SLC6A3HRH3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025233557-A1 | SIGMA-1 RECEPTOR INHIBITING AGENTS FOR TREATING RHEUMATOID ARTHRITIS | UNIVERSIDAD DE GRANADA (ES) | 2025-11-13 | — | — | WO | claimed |
| US-12340996-B2 | Method for rapid on-site detection of fentanyl analogs using a miniature mass spectrometer | CHINESE ACADEMY OF INSPECTION AND QUARANTINE (CN) | 2025-06-24 | — | — | US | claimed |
| WO-2024150963-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 광주과학기술원 | 2024-07-18 | — | — | WO | claimed |
| CN-116916929-A | Novel use of pyrrolopyridine derivatives for the prevention or treatment of inflammatory diseases | 株式会社沃若诺伊 | 2023-10-20 | — | — | CN | claimed |
| US-20230015987-A1 | METHOD FOR RAPID ON-SITE DETECTION OF FENTANYL ANALOGS USING A MINIATURE MASS SPECTROMETER | CHINESE ACADEMY OF INSPECTION AND QUARANTINE (CN) | 2023-01-19 | — | — | US | claimed |
| CN-113767930-A | Biochemical environment-friendly rodenticide and preparation method thereof | 张月荣 | 2021-12-10 | — | — | CN | claimed |
| US-10836874-B2 | High performance cross-linked triblock cationic functionalized polymer for electrochemical applications, methods of making and methods of using | COLORADO SCHOOL OF MINES (US) | 2020-11-17 | — | — | US | claimed |
| CN-105358132-B | Abuse resistant capsules | R.P.谢勒技术有限公司 | 2019-10-15 | — | — | CN | claimed |
| US-20190100633-A1 | HIGH PERFORMANCE CROSS-LINKED TRIBLOCK CATIONIC FUNCTIONALIZED POLYMER FOR ELECTROCHEMICAL APPLICATIONS, METHODS OF MAKING AND METHODS OF USING | UNIVERSITY OF MASSACHUSETTS | 2019-04-04 | — | — | US | claimed |
| CN-108473620-A | Modified conjugated diene polymer and preparation method thereof | 株式会社LG化学 | 2018-08-31 | — | — | CN | claimed |
| CN-108473621-A | Modifier, modified conjugated diene polymer and preparation method thereof | 株式会社LG化学 | 2018-08-31 | — | — | CN | claimed |
| US-20090159448-A1 | ELECTROLYSIS DEVICE, METHOD, AND WASHER USING SUCH A DEVICE | GENERAL ELECTRIC COMPANY (US) | 2009-06-25 | — | — | US | claimed |
| CN-100378108-C | Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them | SUVEN PHARMACEUTICALS LTD (IN) | 2008-04-02 | — | — | CN | claimed |
| EP-1406623-B1 | SUBSTITUTED 1-PHENETHYLPIPERIDINE COMPOUNDS USED AS INTER ALIA ANALGESICS | GRUENENTHAL GMBH (DE) | 2007-12-12 | — | — | EP | claimed |
| CN-1662544-A | Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them | SUVEN PHARMACEUTICALS LTD (IN) | 2005-08-31 | — | — | CN | claimed |
| US-20040171640-A1 | Substituted 1-phenethylpiperidine compounds used as inter alia analgesics | GRUNENTHAL GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| EP-1406623-A1 | SUBSTITUTED 1-PHENETHYLPIPERIDINE COMPOUNDS USED AS INTER ALIA ANALGESICS | Grünenthal GmbH (DE) | 2004-04-14 | — | — | EP | claimed |
| WO-2003004026-A1 | SUBSTITUTED 1-PHENETHYLPIPERIDINE COMPOUNDS USED AS INTER ALIA ANALGESICS | Grünenthal GmbH (DE) | 2003-01-16 | — | — | WO | claimed |
| CN-119735525-B | Amino alkyl nitrile compound and preparation method and application thereof | YUNNAN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-3931195-A | ANTIARRHYTHMIA, ANTISEROTONIN | MEAD JOHNSON & COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171640-A1 | Substituted 1-phenethylpiperidine compounds used as inter alia analgesics | PNMT, OPRK1, OPRM1 | SIGMAR1 30/4885SLC6A3 565/4885HRH3 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.