Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL27675490 | 0.88 | SMN1; SMN2 (0.54) | LMNAPKMAKR1C3MEN1KMT2A | |
| Carbamic Acid SCHEMBL27675440 | 0.87 | AKR1C3 (0.62) | LMNAAKR1C3MEN1KMT2AKDM4E | |
| Carbamic Acid SCHEMBL27693832 | 0.86 | KMT2A (0.73) | PKMAKR1C3MEN1KMT2AKDM4E | |
| Carbamic Acid SCHEMBL27675445 | 0.86 | AKR1C3 (0.61) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| Carbamic Acid SCHEMBL4693159 | 0.83 | AKR1C3 (0.58) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5439640 | 0.76 | MMP1 (0.50) | LMNAPKMMEN1KMT2AMAPT | |
| SCHEMBL5430809 | 0.76 | MMP1 (0.50) | LMNAPKMMEN1KMT2AMAPT | |
| SCHEMBL5435833 | 0.76 | MMP1 (0.50) | LMNAPKMMEN1KMT2AMAPT | |
| SCHEMBL23081190 | 0.75 | AKR1C3 (0.78) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL693455 | 0.74 | KMT2A (1.00) | AKR1C3MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006059-A | Substituted tetrahydroisoquinolines for use as MMP inhibitors, method for the production thereof, and use thereof in the form of medicaments | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-07-25 | — | — | CN | disclosed |