Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL27693832 | 0.88 | KMT2A (0.73) | AKR1C3MEN1KMT2ASMN1; SMN2KDM4E | |
| Carbamic Acid SCHEMBL27675440 | 0.87 | AKR1C3 (0.62) | AKR1C3MEN1KMT2ASMN1; SMN2KDM4E | |
| Carbamic Acid SCHEMBL27675445 | 0.86 | AKR1C3 (0.61) | AKR1C3MEN1KMT2ASMN1; SMN2KDM4E | |
| Carbamic Acid SCHEMBL28763111 | 0.83 | LMNA (0.59) | AKR1C3MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5431774 | 0.76 | HTR6 (0.42) | MEN1KMT2ANPSR1LIPEEPHX2 | |
| SCHEMBL3311307 | 0.76 | HTR6 (0.42) | MEN1KMT2ANPSR1LIPEEPHX2 | |
| SCHEMBL5439605 | 0.76 | HTR6 (0.42) | MEN1KMT2ANPSR1LIPEEPHX2 | |
| SCHEMBL23081190 | 0.75 | AKR1C3 (0.78) | AKR1C3MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31745757 | 0.75 | ESR2 (0.58) | AKR1C3MEN1KMT2AAKR1C1ESR2 | |
| SCHEMBL693455 | 0.74 | KMT2A (1.00) | AKR1C3MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763515-B1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-03-12 | — | — | EP | claimed |