⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28863248 | 0.74 | — | — | |
| Bicarbonate SCHEMBL28863250 | 0.74 | CA2 (0.56) | — | |
| Bicarbonate SCHEMBL8976867 | 0.73 | CYP1A2 (0.47) | — | |
| Hydrazinecarboxamide SCHEMBL10887889 | 0.73 | TSHR (0.83) | — | |
| Hydrazinecarboxamide SCHEMBL3206080 | 0.73 | — | — | |
| Hydrazinecarboxamide SCHEMBL15393 | 0.70 | — | — | |
| SCHEMBL10623380 | 0.70 | NFKB1 (0.54) | — | |
| SCHEMBL64716 | 0.70 | — | — | |
| SCHEMBL20178517 | 0.70 | NFKB1 (0.54) | — | |
| SCHEMBL7258925 | 0.70 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795203-A | Stability for antibody drug conjugate adjusts joint | 辉瑞公司 | 2017-05-31 | — | — | CN | claimed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | claimed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | claimed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | claimed |
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | claimed |
| US-6248752-B1 | Azabicyclooctane compositions and methods for enhancing chemotherapy | SMITH CHARLES DUANE (US) | 2001-06-19 | — | — | US | claimed |
| US-4232032-A | GROWTH PROMOTERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-11-04 | — | — | US | claimed |
| CN-104744732-B | Optical film, polarizing plate and liquid crystal display device using the same, and compound | 富士胶片株式会社 | 2020-03-03 | — | — | CN | disclosed |
| CN-106795203-A | Stability for antibody drug conjugate adjusts joint | 辉瑞公司 | 2017-05-31 | — | — | CN | disclosed |
| US-20150185368-A1 | OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2015-07-02 | — | — | US | disclosed |
| EP-1674526-B9 | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| EP-1674526-B1 | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2012-12-05 | — | — | EP | disclosed |
| CN-101218214-B | Liquid crystal compound, liquid crystal composition, thin film, and liquid crystal display | FUJI PHOTO FILM CO LTD | 2011-08-24 | — | — | CN | disclosed |
| US-4883793-A | Hydrazinocarbonyloxylabdanes for treating cardiac failure | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0341571-A1 | Hydrazinocarbonyloxylabdanes, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-11-15 | — | — | EP | disclosed |
| CN-1035283-A | Process for producing tert-butyl 3-oxobutyrate and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1989-09-06 | — | — | CN | disclosed |
| US-4806637-A | 6-(Hydroxyethyl)-2-(heterocyclylthio)-penem-3-carboxylates | SCHERING CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |
| US-4806637-A | 6-(Hydroxyethyl)-2-(heterocyclylthio)-penem-3-carboxylates | SCHERING CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |
| US-4801521-A | Method for processing silver halide color photographic material with a color developer comprising a hydrazine derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| US-4127576-A | NARCOSIS POTENTIATING AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1978-11-28 | — | — | US | disclosed |