Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778138 | 0.88 | ALDH1A1 (0.55) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL8064549 | 0.88 | ALDH1A1 (0.55) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL11539935 | 0.85 | ALDH1A1 (0.53) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL9153407 | 0.82 | ALDH1A1 (0.51) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL21715106 | 0.81 | HSD11B1 (0.71) | HSD11B1ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL3625848 | 0.81 | ALDH1A1 (0.51) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL1332360 | 0.81 | ALDH1A1 (0.51) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL11590919 | 0.80 | ALDH1A1 (0.50) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL1184723 | 0.80 | ALDH1A1 (0.50) | HSD11B1ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL31483318 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85105066-A | The production of condensed seven-membered compounds, their and application | — | 1986-12-31 | — | — | CN | disclosed |