Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631343 | 0.91 | HSD11B1 (0.60) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| Hydrochloric Acid SCHEMBL9630160 | 0.90 | HSD11B1 (0.59) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL21501052 | 0.89 | HSD11B1 (0.67) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL11026630 | 0.84 | ALDH1A1 (0.54) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL20246861 | 0.84 | ALDH1A1 (0.82) | HSD11B1ALDH1A1GAAPOLBKMT2A | |
| SCHEMBL11778138 | 0.84 | ALDH1A1 (0.55) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL8064549 | 0.84 | ALDH1A1 (0.55) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL28763753 | 0.81 | HSD11B1 (0.51) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL11539935 | 0.81 | ALDH1A1 (0.53) | HSD11B1ALDH1A1GAAPOLBMAPT | |
| SCHEMBL8283042 | 0.81 | HSD11B1 (0.49) | HSD11B1ALDH1A1GAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696617-B2 | Method for alcoholysis of amide | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD (CN) | 2020-06-30 | — | — | US | disclosed |
| US-20200055807-A1 | METHOD FOR ALCOHOLYSIS OF AMIDE | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD (CN) | 2020-02-20 | — | — | US | disclosed |
| CN-107417594-A | A kind of method of acid amides alcoholysis | 凯莱英医药集团（天津）股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055807-A1 | METHOD FOR ALCOHOLYSIS OF AMIDE | ADH1A, ADH5, ADH1C | HSD11B1 779/4885ALDH1A1 43/4885GAA 820/4885 |
| US-10696617-B2 | Method for alcoholysis of amide | ADH5, ADH1A, ADH1C | HSD11B1 766/4885ALDH1A1 91/4885GAA 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.