Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680341 | 0.78 | HTT (0.44) | ALOX5GLSHDAC1HDAC3TSHR | |
| SCHEMBL27756817 | 0.72 | ALOX5 (0.37) | ALOX5GLSTSHRTP53MAPT | |
| SCHEMBL6614649 | 0.71 | ALOX5 (0.42) | ALOX5GLSHDAC2HDAC1HDAC3 | |
| SCHEMBL20993292 | 0.71 | ALOX5 (0.38) | ALOX5CTSCTSHRCES2CES1 | |
| SCHEMBL17829522 | 0.71 | NPC1 (0.43) | ALOX5TSHRCES2CES1KEAP1 | |
| SCHEMBL6464486 | 0.68 | ALOX5 (0.50) | ALOX5GLSTSHRCES2CES1 | |
| SCHEMBL10210730 | 0.68 | ALOX5 (0.50) | ALOX5GLSTSHRCES2CES1 | |
| SCHEMBL20899846 | 0.68 | GAA (0.42) | ALOX5GLSTSHRCES2CES1 | |
| SCHEMBL7605356 | 0.67 | MAPT (0.47) | ALOX5TSHRMAPTRAB9A | |
| SCHEMBL7411580 | 0.67 | MAPT (0.47) | ALOX5TSHRMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014578-B | Triazole derivative or salt thereof | ASTELLAS PHARMA INC | 2011-01-19 | — | — | CN | disclosed |
| CN-101014578-A | Triazole derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2007-08-08 | — | — | CN | disclosed |