Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170178 | 0.82 | HTT (0.45) | HTTTSHRGLAL3MBTL1CA2 | |
| SCHEMBL28764512 | 0.78 | ALOX5 (0.40) | TSHRGLSHDAC3ALOX5HDAC1 | |
| SCHEMBL6521155 | 0.78 | HDAC8 (0.49) | HTTHDAC3HDAC1HDAC11HDAC8 | |
| SCHEMBL9093734 | 0.77 | HDAC1 (0.43) | HTTTSHRGLAL3MBTL1HDAC3 | |
| SCHEMBL9000597 | 0.77 | HDAC1 (0.43) | HTTTSHRGLAL3MBTL1HDAC3 | |
| SCHEMBL9000645 | 0.76 | ZDHHC7 (0.45) | HTTTSHRGLAL3MBTL1HDAC3 | |
| SCHEMBL23695275 | 0.75 | CA2 (0.43) | HTTTSHRGLAL3MBTL1CA2 | |
| SCHEMBL9567286 | 0.73 | HDAC1 (0.40) | HTTTSHRGLAL3MBTL1HDAC3 | |
| SCHEMBL7269210 | 0.73 | NPC1 (0.50) | HTTTSHRGLAL3MBTL1HDAC3 | |
| SCHEMBL7276887 | 0.73 | NPC1 (0.50) | HTTTSHRGLAL3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014578-B | Triazole derivative or salt thereof | ASTELLAS PHARMA INC | 2011-01-19 | — | — | CN | disclosed |
| CN-101014578-A | Triazole derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2007-08-08 | — | — | CN | disclosed |