Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545116 | 0.77 | MEN1 (0.70) | MEN1KMT2AALOX5 | |
| SCHEMBL22557901 | 0.77 | MEN1 (0.70) | MEN1KMT2AALOX5 | |
| SCHEMBL3663216 | 0.77 | CCNT1 (0.56) | CHEK2FYNCHEK1EGLN1HSD17B1 | |
| SCHEMBL28723831 | 0.76 | KMT2A (0.45) | MEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL982016 | 0.73 | MAP4K4 (0.68) | MEN1MAP4K4HSD17B1HSD17B2MKNK1 | |
| SCHEMBL27484485 | 0.72 | MEN1 (0.61) | MEN1KMT2ARXRARXRB | |
| SCHEMBL22347922 | 0.72 | RXRA (0.64) | MEN1KMT2ARXRARXRB | |
| SCHEMBL16512756 | 0.71 | ESR2 (0.60) | CHEK2FYNMAP4K4EGLN1HSD17B1 | |
| SCHEMBL3641396 | 0.70 | MEN1 (0.76) | MEN1KMT2A | |
| SCHEMBL4457917 | 0.70 | MEN1 (0.53) | MEN1KMT2ACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108350028-B | Peptide macrocycles against Acinetobacter baumannii | 豪夫迈·罗氏有限公司 | 2021-12-07 | — | — | CN | disclosed |