Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27542200 | 0.82 | LOXL2 (0.51) | FFAR1PDPK1ABL1BCRPTGDR2 | |
| SCHEMBL2303493 | 0.78 | KAT6A (0.55) | FFAR1PDPK1ABL1BCRPTGDR2 | |
| SCHEMBL11116139 | 0.78 | PDPK1 (0.51) | FFAR1PDPK1ABL1BCRPTGDR2 | |
| SCHEMBL1980934 | 0.77 | DYRK1A (0.57) | PDPK1ABL1BCRCYP2A6CTSA | |
| SCHEMBL29462071 | 0.77 | DYRK1A (0.57) | PDPK1ABL1BCRCYP2A6CTSA | |
| SCHEMBL11115774 | 0.77 | PDPK1 (0.50) | FFAR1PDPK1ABL1BCRPTGDR2 | |
| SCHEMBL15805858 | 0.76 | PDPK1 (0.72) | FFAR1PDPK1PTGDR2KAT6AHDAC2 | |
| SCHEMBL4748362 | 0.76 | FAAH (0.65) | HDAC6 | |
| 2-Phenylthiazole SCHEMBL28287735 | 0.75 | PDPK1 (0.78) | FFAR1PDPK1ABL1BCRPTGDR2 | |
| SCHEMBL2152506 | 0.75 | NOTUM (0.57) | FFAR1PDPK1PTGDR2LOXL2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |