Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13994549 | 0.85 | HCAR2 (0.49) | CYP3A4ALDH1A1PTGES | |
| SCHEMBL13994546 | 0.85 | HCAR2 (0.49) | CYP3A4ALDH1A1PTGES | |
| SCHEMBL12437265 | 0.82 | TDP1 (0.46) | HDAC1HDAC6MEN1KMT2AHPGD | |
| SCHEMBL2215260 | 0.82 | TDP1 (0.46) | HDAC1HDAC6MEN1KMT2AHPGD | |
| SCHEMBL1968848 | 0.79 | NAAA (0.48) | HDAC1HDAC6SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL2221132 | 0.79 | NAAA (0.48) | HDAC1HDAC6SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL584760 | 0.76 | ALDH1A1 (0.52) | THRBHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL2384186 | 0.76 | ALDH1A1 (0.52) | THRBHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL584761 | 0.76 | ALDH1A1 (0.52) | THRBHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL28295175 | 0.74 | MMP1 (0.42) | MEN1KMT2ATP53SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950335-A | Novel biaromatic compounds which activate PPAR.gamma.-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-04-18 | — | — | CN | disclosed |