Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15696056 | 0.78 | TLR8 (0.33) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL28124885 | 0.77 | CTRC (0.39) | CTRCHTR2AHTR2CHTR2BTYR | |
| SCHEMBL27777055 | 0.76 | CTRC (0.41) | CTRCHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL27857665 | 0.74 | CTRC (0.37) | CTRCHTR2AHTR2CHTR2BHTT | |
| SCHEMBL22791948 | 0.72 | LIPG (0.40) | CTRCHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL12802233 | 0.72 | CYP3A4 (0.42) | THRATHRBTYR | |
| SCHEMBL27754223 | 0.72 | ALDH1A1 (0.41) | CTRCKMT2AALDH1A1HTT | |
| SCHEMBL1704724 | 0.72 | CTRC (0.40) | CTRCALDH1A1TLR8 | |
| SCHEMBL16828251 | 0.71 | TYR (0.38) | CTRCHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL19310672 | 0.71 | TDP1 (0.35) | CTRCHTR2AHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |