Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652903 | 0.89 | HDAC6 (0.40) | HDAC6F10NPC1RAB9APKM | |
| SCHEMBL4183295 | 0.81 | ESR2 (0.50) | HDAC6ESR2 | |
| SCHEMBL25796673 | 0.78 | F10 (0.41) | F10PRMT5WDR77ALDH1A1 | |
| SCHEMBL13673816 | 0.76 | ALDH1A1 (0.56) | HDAC6F2TPSAB1TPSD1TPSG1 | |
| SCHEMBL20741820 | 0.76 | HDAC6 (0.47) | HDAC6F2TPSAB1TPSD1TPSG1 | |
| SCHEMBL3441635 | 0.75 | HDAC6 (0.43) | HDAC6F2TPSAB1TPSD1TPSG1 | |
| SCHEMBL3441449 | 0.74 | HDAC6 (0.42) | HDAC6F2TPSAB1TPSD1TPSG1 | |
| SCHEMBL28956427 | 0.72 | HDAC6 (0.41) | HDAC6F2TPSAB1TPSD1TPSG1 | |
| SCHEMBL5244207 | 0.72 | CCR2 (0.45) | HDAC6F10NPC1RAB9APKM | |
| SCHEMBL3441436 | 0.71 | HDAC6 (0.39) | HDAC6F2TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068804-A | Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2007-11-07 | — | — | CN | disclosed |