Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711656 | 0.73 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL28583380 | 0.72 | LMNA (0.40) | PDE4AMEN1KMT2APTGS1MAPT | |
| SCHEMBL16664291 | 0.70 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL16499791 | 0.69 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL27798054 | 0.68 | ERN1 (0.40) | MAPTHPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL288453 | 0.68 | ERN1 (0.41) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL2918748 | 0.67 | AKR1C3 (0.63) | PDE4AMEN1KMT2APTGS1MAPT | |
| SCHEMBL4949023 | 0.67 | AKR1C3 (0.63) | PDE4AMEN1KMT2APTGS1MAPT | |
| SCHEMBL7348404 | 0.67 | AKR1C3 (0.63) | PDE4AMEN1KMT2APTGS1MAPT | |
| SCHEMBL27644465 | 0.66 | ALDH1A1 (0.50) | PDE4BPDE4APDE4CPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061105-A | Potentiators of glutamate receptors | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |