Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.39 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587166 | 0.81 | GABRA1 (0.48) | PDE4BPDE4APDE4CPDE4DESR1 | |
| SCHEMBL27705273 | 0.79 | PDE4A (0.41) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL28770616 | 0.73 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL27691522 | 0.73 | MAPK1 (0.34) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL27691695 | 0.73 | ADRB2 (0.38) | — | |
| SCHEMBL27691527 | 0.73 | ERN1 (0.32) | — | |
| SCHEMBL28177274 | 0.72 | ERN1 (0.45) | MAPTKDM4EPOLBGAARECQL | |
| SCHEMBL4378835 | 0.71 | GABRA1 (0.58) | MAPTKDM4EPOLBRECQLMEN1 | |
| SCHEMBL1535884 | 0.70 | BACE1 (0.54) | PDE4BPDE4APDE4CPDE4DESR1 | |
| SCHEMBL16096807 | 0.70 | ERN1 (0.48) | PDE4BPDE4APDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061105-A | Potentiators of glutamate receptors | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |