Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810643 | 0.92 | TLR8 (0.44) | TLR8TLR7BRD4 | |
| SCHEMBL28809651 | 0.86 | SIGMAR1 (0.39) | TLR8TLR7 | |
| SCHEMBL22771035 | 0.85 | TLR8 (0.57) | TLR8TLR7 | |
| SCHEMBL18041395 | 0.83 | TLR8 (0.45) | TLR8TLR7 | |
| SCHEMBL24699321 | 0.81 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL28772134 | 0.78 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL22771108 | 0.77 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL19618668 | 0.76 | TLR8 (0.47) | TLR8TLR7 | |
| SCHEMBL18041439 | 0.76 | TLR8 (0.50) | TLR8TLR7 | |
| SCHEMBL24698182 | 0.76 | TLR8 (0.57) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585390-A | Aminobenzazepine compounds, immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2022-06-03 | — | — | CN | disclosed |