Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790388 | 0.83 | TDP1 (0.44) | TDP1TSHRALDH1A1ATMCYP2C19 | |
| SCHEMBL1790386 | 0.81 | ALDH1A1 (0.45) | TDP1TSHRALDH1A1ATMCYP2C19 | |
| SCHEMBL29199324 | 0.77 | TDP1 (0.64) | TDP1TSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL260960 | 0.77 | TDP1 (0.64) | TDP1TSHRALDH1A1HSD17B10MAPT | |
| Hydrogen Peroxide SCHEMBL28425777 | 0.77 | TDP1 (0.64) | TDP1TSHRALDH1A1HSD17B10MAPT | |
| Hydrogen Peroxide SCHEMBL28474133 | 0.77 | TDP1 (0.64) | TDP1TSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL1953844 | 0.77 | TSHR (0.59) | TDP1TSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL1786261 | 0.77 | TSHR (0.59) | TDP1TSHRALDH1A1HSD17B10MAPT | |
| Bicarbonate SCHEMBL28291099 | 0.76 | ALDH1A1 (0.56) | TDP1TSHRALDH1A1ATMMAPT | |
| SCHEMBL18567268 | 0.75 | TDP1 (0.69) | TDP1TSHRALDH1A1HSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101318887-B | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND | 2011-03-23 | — | — | CN | claimed |
| CN-101318887-A | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND (CN) | 2008-12-10 | — | — | CN | claimed |
| CN-101318887-B | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND | 2011-03-23 | — | — | CN | disclosed |
| CN-101318887-A | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND (CN) | 2008-12-10 | — | — | CN | disclosed |