Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769706 | 0.82 | KCNH2 (0.42) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL4273650 | 0.80 | KCNH2 (0.48) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL27724748 | 0.79 | KCNH2 (0.57) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL27724578 | 0.76 | NR3C1 (0.52) | — | |
| SCHEMBL27724735 | 0.76 | KCNH2 (0.51) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL24509143 | 0.75 | KCNH2 (0.72) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL4272116 | 0.75 | HRH1 (0.43) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL28080209 | 0.72 | SMN1; SMN2 (0.47) | KCNH2LMNACHRM4CHRM3 | |
| SCHEMBL27704252 | 0.71 | KCNH2 (0.55) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL27724540 | 0.71 | L3MBTL1 (0.51) | DHODHHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193869-A | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-04 | — | — | CN | claimed |
| CN-101193869-B | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA | 2011-03-02 | — | — | CN | disclosed |
| CN-101193869-A | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-04 | — | — | CN | disclosed |