SCHEMBL28774174

SCHEMBL28774174

C[C@H](N)CCOC(=O)CC(O)C(=O)OCC[C@H](C)N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
GABRA4 P48169 2/20 0.36
GABRE P78334 2/20 0.36
GABRA6 Q16445 2/20 0.36
GABRG1 Q8N1C3 2/20 0.36
GABRG3 Q99928 2/20 0.36
GABRQ Q9UN88 2/20 0.36
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28774169 1.00 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28208865 0.85 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28208885 0.85 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL296699 0.85 CYP19A1 (0.44) CYP19A1
SCHEMBL11092928 0.80 NAAA (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15972488 0.78 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28232472 0.78 L3MBTL1 (0.38)
SCHEMBL2231276 0.76 NAAA (0.42)
SCHEMBL29929707 0.75 NAAA (0.43) CYP19A1
SCHEMBL21409612 0.75 NAAA (0.43) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107793320-B Method for preparing single-configuration 3-amino-1-butanol by chiral resolution 上海迪赛诺药业股份有限公司 2022-06-28 CN claimed
CN-107793320-B Method for preparing single-configuration 3-amino-1-butanol by chiral resolution 上海迪赛诺药业股份有限公司 2022-06-28 CN disclosed