Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | CBX7 | O95931 | 1/20 | 0.30 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.30 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.30 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862542 | 0.81 | HSD17B10 (0.32) | HTR2CPGRHSD17B10ALPG | |
| SCHEMBL27774969 | 0.68 | CNR2 (0.31) | — | |
| SCHEMBL27590615 | 0.67 | AHR (0.35) | HSD17B10KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL754751 | 0.67 | PGR (0.42) | PGRMAP3K14CYP46A1CBX7CDYL2 | |
| SCHEMBL27756139 | 0.66 | KCNH2 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27980988 | 0.66 | KMT2A (0.31) | — | |
| SCHEMBL27721773 | 0.65 | RET (0.31) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27353793 | 0.64 | IDO1 (0.36) | PGRMAP3K14CBX7CDYL2CDYL | |
| SCHEMBL27981196 | 0.63 | KMT2A (0.31) | — | |
| SCHEMBL20708104 | 0.61 | PGR (0.40) | HTR2CPGRHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379048-A | Benzo oxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | CN | disclosed |