Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348792 | 0.85 | FAAH (0.46) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL27748649 | 0.85 | PTGS2 (0.46) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL27730616 | 0.84 | PTGS2 (0.62) | PTGS2CXCR1CXCR2PTGS1LMNA | |
| SCHEMBL9257901 | 0.80 | PTGS2 (0.46) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL28477579 | 0.79 | PTGS2 (0.47) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL3894104 | 0.78 | CXCR1 (0.70) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL1028462 | 0.78 | CXCR1 (0.70) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL1028463 | 0.78 | CXCR1 (0.70) | FAAHPTGS2CXCR1CXCR2PTGS1 | |
| SCHEMBL2291864 | 0.75 | CYP1A2 (0.48) | PTGS2LMNAALOX5TSHR | |
| SCHEMBL28776369 | 0.75 | PTGS2 (0.39) | FAAHPTGS2CXCR1CXCR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930137-B | Benzothiazepine and benzoazepine compounds | ASAHI KASEI PHARMA CORP | 2011-07-20 | — | — | CN | disclosed |
| CN-100494185-C | Novel quaternary ammonium compounds | ASAHI KASEI PHARMA CORP (JP) | 2009-06-03 | — | — | CN | disclosed |