Acetylthiocholine

Acetylthiocholine

SCHEMBL28776641

CC(=O)SCC[N+](C)(C)C.C[N+](C)(C)CCS

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.79
POLB P06746 1/20 0.76
BLM P54132 1/20 0.76
ATM Q13315 1/20 0.76
ACHE P22303 5/20 0.35
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
SLC6A4 P31645 1/20 0.34
PGR P06401 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
HTR1A P08908 1/20 0.34
CHRNB2 P17787 1/20 0.34
TBXA2R P21731 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylthiocholine SCHEMBL3720144 0.98 CYP2C19 (0.76) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL8006744 0.94 CYP2C19 (0.70) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL77666 0.89 CYP2C19 (1.00) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL27356791 0.87 CYP2C19 (0.95) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL1276372 0.87 BLM (1.00) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL7172548 0.87 CYP2C19 (0.95) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL4318618 0.87 CYP2C19 (0.95) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL16322376 0.87 CYP2C19 (0.95) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL4318613 0.87 CYP2C19 (0.95) CYP2C19POLBBLMATMACHE
Acetylthiocholine SCHEMBL400577 0.87 CYP2C19 (0.95) CYP2C19POLBBLMATMACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101282923-A 2, 5-bis-diamine- [1,4] benzoquinone derivative UNIV BOLOGNA ALMA MATER (IT) 2008-10-08 CN disclosed