Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25667539 | 0.89 | ENPP2 (0.54) | GSK3BCA12CA1CA2CA9 | |
| SCHEMBL265232 | 0.87 | PTGS2 (0.69) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL4920494 | 0.81 | PTGS2 (0.73) | PTGS2AVPR2GPR27FAAHMGLL | |
| SCHEMBL3245767 | 0.81 | MEN1 (0.58) | GSK3BPTGS2PTGS1ALDH1A1MAPK1 | |
| SCHEMBL27710777 | 0.81 | SOS1 (0.72) | PTGS2AVPR2GPR27PTGS1CA12 | |
| SCHEMBL4191619 | 0.81 | XDH (0.54) | GSK3BPTGS2PTGS1KIF11 | |
| SCHEMBL5052857 | 0.80 | PTGS2 (0.74) | PTGS2PTGS1KIF11ALDH1A1CYP3A4 | |
| SCHEMBL27497103 | 0.79 | CA1 (0.75) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL9229025 | 0.79 | CES1 (0.53) | CES1CA12CA1CA2CA3 | |
| SCHEMBL17492848 | 0.78 | GSK3B (0.45) | GSK3BPTGS2CES1AVPR2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014453-A1 | INHIBITORS OF JANUS KINASES | MERCK & CO., INC. (US) | 2010-02-04 | — | — | WO | disclosed |