Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.44 |
| ▸ | CES1 | P23141 | 9/20 | 0.44 |
| ▸ | CES2 | O00748 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024069 | 0.93 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL11320198 | 0.77 | DNM1 (0.44) | FAAHCES1CES2DNM1 | |
| SCHEMBL11323157 | 0.77 | DNM1 (0.44) | FAAHCES1CES2DNM1 | |
| SCHEMBL30234581 | 0.77 | DNM1 (0.44) | FAAHCES1CES2DNM1 | |
| SCHEMBL11324407 | 0.77 | DNM1 (0.44) | FAAHCES1CES2DNM1 | |
| SCHEMBL4321071 | 0.77 | DNM1 (0.44) | FAAHCES1CES2DNM1 | |
| SCHEMBL2750539 | 0.77 | DNM1 (0.42) | CES1CES2DNM1 | |
| SCHEMBL4891467 | 0.76 | DNM1 (0.49) | DNM1 | |
| SCHEMBL6669138 | 0.76 | DNM1 (0.43) | FAAHCES1CES2DNM1 | |
| SCHEMBL3928482 | 0.76 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621243-A | Sulfonamide derivative and application thereof | 上海拓界生物医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |