Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778485 | 0.90 | FAAH (0.61) | FAAHMEN1KMT2ACCR3NPC1 | |
| SCHEMBL28778465 | 0.90 | SMN1; SMN2 (0.61) | FAAHMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28778471 | 0.85 | FAAH (0.61) | FAAHKMT2ASMN1; SMN2POLB | |
| SCHEMBL20219013 | 0.84 | KDM4E (0.62) | MEN1KMT2ACCR3SMN1; SMN2HSD17B10 | |
| SCHEMBL28778498 | 0.83 | FAAH (0.64) | FAAHKMT2A | |
| SCHEMBL20236305 | 0.81 | FAAH (0.64) | FAAHSMN1; SMN2HSD17B10NPC1POLB | |
| SCHEMBL28778469 | 0.79 | FAAH (0.77) | FAAHNPC1TP53POLBRAB9A | |
| SCHEMBL28778484 | 0.79 | SMN1; SMN2 (0.75) | FAAHMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29769956 | 0.74 | RAB9A (0.70) | FAAHMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13148325 | 0.74 | FAAH (0.86) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751874-A | 1-benzyl-4-ethylpiperazine derivatives as TRPV4-KCa2.3 coupling promoting agents and application thereof | 江南大学 | 2022-07-15 | — | — | CN | disclosed |