Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.63 |
| ▸ | PRKAG1 | P54619 | 8/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.63 |
| ▸ | PRKAA1 | Q13131 | 8/20 | 0.63 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.63 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.63 |
| ▸ | PRKAB1 | Q9Y478 | 8/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778485 | 0.89 | FAAH (0.61) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28778471 | 0.88 | FAAH (0.61) | FAAHHTTKMT2ATDP1TRPV1 | |
| SCHEMBL28778491 | 0.83 | FAAH (0.58) | FAAHKMT2A | |
| SCHEMBL28778465 | 0.82 | SMN1; SMN2 (0.61) | FAAHKMT2ATRPV1 | |
| SCHEMBL17453740 | 0.78 | FAAH (0.73) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28778469 | 0.77 | FAAH (0.77) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29769956 | 0.77 | RAB9A (0.70) | FAAHKMT2A | |
| SCHEMBL28363510 | 0.76 | POLB (0.76) | HTTKMT2ATDP1TRPV1 | |
| SCHEMBL23246064 | 0.75 | RHOC (0.60) | KMT2ATRPV1 | |
| SCHEMBL24529879 | 0.75 | PRKAB2 (0.56) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751874-A | 1-benzyl-4-ethylpiperazine derivatives as TRPV4-KCa2.3 coupling promoting agents and application thereof | 江南大学 | 2022-07-15 | — | — | CN | disclosed |