⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491971 | 0.72 | — | — | |
| SCHEMBL15285328 | 0.67 | — | — | |
| SCHEMBL234461 | 0.64 | ALDH1A1 (0.58) | — | |
| SCHEMBL30853512 | 0.64 | TDP1 (0.61) | — | |
| Formaldehyde SCHEMBL28680174 | 0.59 | CYP2A6 (0.62) | — | |
| SCHEMBL27660168 | 0.59 | ALDH1A1 (0.52) | — | |
| SCHEMBL17366351 | 0.57 | ALDH1A1 (0.36) | — | |
| SCHEMBL24385153 | 0.57 | ALDH1A1 (0.50) | — | |
| Nitrosobenzene SCHEMBL3176061 | 0.57 | — | — | |
| Nitrosobenzene SCHEMBL103117 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017146456-A1 | CRYSTALLINE POLYMER AND PREPARATION METHOD THEREFOR | 광주과학기술원 | 2017-08-31 | — | — | WO | disclosed |
| US-7785616-B2 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2010-08-31 | — | — | US | disclosed |
| US-7696247-B2 | Lipid-based nitric oxide donors | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20100062055-A1 | LIPID-BASED NITRIC OXIDE DONORS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| EP-1343485-B1 | Drug delivery system comprising a lipid-based nitric oxide donor | BOSTON SCIENT LTD (BB) | 2010-01-27 | — | — | EP | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-20070258942-A1 | C-Nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
| US-7259250-B2 | C-nitroso compounds and use thereof | DUKE UNIVERSITY (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1330425-B1 | C-NITROSO COMPOUNDS AND USE THEREOF | UNIV DUKE (US) | 2007-06-13 | — | — | EP | disclosed |
| US-20040006059-A1 | C-nitroso compounds and use thereof | DUKE UNIVERSITY | 2004-01-08 | — | — | US | disclosed |
| US-20030176668-A1 | C-nitroso compounds and use thereof | STAMLER JONATHAN S (US) | 2003-09-18 | — | — | US | disclosed |
| EP-1343485-A2 | LIPID-BASED NITRIC OXIDE DONORS | Boston Scientific Limited (BB) | 2003-09-17 | — | — | EP | disclosed |
| EP-1330425-A2 | C-NITROSO COMPOUNDS AND USE THEREOF | DUKE UNIVERSITY (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6538116-B2 | For therapy of inflammatory or painful disorder | DUKE UNIVERSITY | 2003-03-25 | — | — | US | disclosed |
| WO-2002056874-A2 | LIPID-BASED NITRIC OXIDE DONORS | SCIMED LIFE SYSTEMS, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| US-20020082221-A1 | Lipid-based nitric oxide donors | SCIMED LIFE SYSTEMS, INC. | 2002-06-27 | — | — | US | disclosed |
| US-20020077506-A1 | For therapy of inflammatory or painful disorder | STAMLER JONATHAN S (US) | 2002-06-20 | — | — | US | disclosed |
| WO-2002034705-A2 | C-NITROSO COMPOUNDS AND USE THEREOF | DUKE UNIVERSITY (US) | 2002-05-02 | — | — | WO | disclosed |
| US-6359182-B1 | VASCULAR SYSTEM RELAXATION; ANTIINFLAMMATORY AGENTS; ANALGESICS | DUKE UNIVERSITY | 2002-03-19 | — | — | US | disclosed |