Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716195 | 0.92 | F2 (0.48) | PPARGPPARALTA4HBCHEMAPT | |
| SCHEMBL27875629 | 0.86 | BCHE (0.49) | BCHELMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL7167442 | 0.86 | ALOX5 (0.49) | BCHELMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL3090270 | 0.84 | FFAR1 (0.48) | BCHELMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL38662261 | 0.83 | ALDH1A1 (0.54) | PPARGPPARALTA4HCYP1A2CYP2C19 | |
| SCHEMBL832850 | 0.81 | EPHX1 (0.48) | CYP1A2PTGS1SLC6A2SLC6A3MAOA | |
| SCHEMBL8505924 | 0.81 | LMNA (0.53) | BCHELMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8505922 | 0.81 | LMNA (0.53) | BCHELMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL2844054 | 0.81 | LMNA (0.53) | BCHELMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8618057 | 0.81 | BCHE (0.56) | LTA4HBCHEFFAR1FFAR4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346358-A | Estrogen modulators | PFIZER PROD INC (US) | 2009-01-14 | — | — | CN | disclosed |