Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27687137 | 0.78 | LMNA (0.50) | ADORA3L3MBTL1LMNAPOLBRAB9A | |
| SCHEMBL6412460 | 0.75 | HCAR2 (0.50) | SMN1; SMN2DRD2DRD4DRD3ADORA3 | |
| SCHEMBL5904032 | 0.75 | COMT (0.54) | SMN1; SMN2DRD2DRD4DRD3ADORA3 | |
| SCHEMBL27758320 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2DRD2DRD4DRD3ADORA3 | |
| SCHEMBL624712 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2DRD2DRD4DRD3ADORA3 | |
| SCHEMBL14400727 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2DRD2DRD4DRD3ADORA3 | |
| SCHEMBL6412673 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2DRD2DRD4DRD3ADORA3 | |
| SCHEMBL28013856 | 0.74 | MAPT (0.48) | KMT2AMEN1MAPTRAB9AALOX15 | |
| SCHEMBL27880655 | 0.74 | CYP2D6 (0.60) | DRD2DRD4ALDH1A1 | |
| SCHEMBL6418397 | 0.73 | KDM4E (0.47) | SMN1; SMN2DRD2DRD4DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553232-A | Kinase inhibitors useful for the treatment of proliferative diseases | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-10-07 | — | — | CN | disclosed |