Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418397 | 0.99 | KDM4E (0.47) | SMN1; SMN2HCAR2HCAR3KDM4EALDH1A1 | |
| SCHEMBL6412460 | 0.96 | HCAR2 (0.50) | SMN1; SMN2HCAR2HCAR3KDM4EALDH1A1 | |
| SCHEMBL14400727 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1GAADRD2 | |
| SCHEMBL5904032 | 0.78 | COMT (0.54) | SMN1; SMN2KDM4EALDH1A1GAADRD2 | |
| SCHEMBL18010760 | 0.78 | HCAR2 (0.60) | HCAR2HCAR3COMT | |
| SCHEMBL624712 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL18106980 | 0.76 | L3MBTL1 (0.54) | HCAR2HCAR3COMTPOLBL3MBTL1 | |
| SCHEMBL6414035 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1GAAPOLB | |
| SCHEMBL27540721 | 0.75 | HCAR2 (0.49) | HCAR2HCAR3LMNAMAPT | |
| SCHEMBL7434998 | 0.73 | MAPT (0.49) | SMN1; SMN2KDM4EALDH1A1GAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | WADA KATSUAKI (JP) | 2005-03-03 | — | — | US | disclosed |
| US-6593358-B1 | Method for controlling pests, comprising the step of allowing a pesticidally effective amount of one or more compounds selected from the group consisting of one or more compounds of the formula (Ia) according to claim 2 and one or compounds | NIHON BAYER AGROCHEM K.K. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1200425-A1 | THIENYL-PYRAZOLES AND THEIR USE FOR CONTROLLING PESTS | NIHON BAYER AGROCHEM K.K. (JP) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005787-A1 | THIENYL-PYRAZOLES AND THEIR USE FOR CONTROLLING PESTS | NIHON BAYER AGROCHEM K.K. (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | CBR3, C1S, CYP4B1 | SMN1; SMN2 4328/4885HCAR2 1718/4885HCAR3 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.