Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996630 | 0.90 | REN (0.42) | RENCHEK1CDK2AP1SCN5ASCN9A | |
| SCHEMBL3616993 | 0.90 | REN (0.42) | RENCHEK1CDK2AP1SCN5ASCN9A | |
| SCHEMBL4752797 | 0.82 | KIF11 (0.46) | RENCHEK1CDK2AP1 | |
| SCHEMBL3605975 | 0.82 | REN (0.45) | REN | |
| SCHEMBL3605969 | 0.82 | REN (0.45) | REN | |
| SCHEMBL28787499 | 0.82 | REN (0.53) | RENCHEK1CDK2AP1SCN5ASCN9A | |
| SCHEMBL3613977 | 0.82 | REN (0.42) | RENSCN5ASCN9A | |
| SCHEMBL3610057 | 0.82 | REN (0.42) | RENSCN5ASCN9A | |
| SCHEMBL1866028 | 0.81 | REN (0.46) | REN | |
| SCHEMBL1866030 | 0.81 | REN (0.46) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356156-B | Aspartic protease inhibitors | VITAE PHARMACEUTICALS INC | 2012-12-05 | — | — | CN | disclosed |
| CN-101356156-A | Aspartic protease inhibitors | VITAE PHARMACEUTICALS INC (US) | 2009-01-28 | — | — | CN | disclosed |