Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | CDC7 | O00311 | 2/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434197 | 0.86 | MDM2 (0.67) | RAB9AMAPTNPC1KDM4ENFKB1 | |
| SCHEMBL29647658 | 0.82 | P2RX7 (0.54) | RAB9AMAPTNPC1KDM4EPOLB | |
| SCHEMBL28779577 | 0.82 | P2RX7 (0.54) | RAB9AMAPTNPC1KDM4EPOLB | |
| SCHEMBL3517715 | 0.82 | RAB9A (0.59) | DCTPP1RAB9AMAPTNPC1KDM4E | |
| SCHEMBL3228832 | 0.82 | DCTPP1 (0.64) | DCTPP1RAB9AMAPTNPC1KDM4E | |
| SCHEMBL25866687 | 0.80 | SMN1; SMN2 (0.65) | RAB9AMAPTNPC1KDM4EMEN1 | |
| SCHEMBL31437233 | 0.79 | KDM4E (0.60) | DCTPP1RAB9AMAPTNPC1KDM4E | |
| SCHEMBL4426818 | 0.79 | RAB9A (0.60) | RAB9AMAPTNPC1KDM4EPOLB | |
| SCHEMBL31437286 | 0.79 | KDM4E (0.60) | DCTPP1RAB9AMAPTNPC1KDM4E | |
| SCHEMBL26674748 | 0.79 | KDM4E (0.60) | DCTPP1RAB9AMAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156672-B | Preparation method of semicarbazide compound and application of prepared compound | 浙江师范大学 | 2022-06-10 | — | — | CN | claimed |