Quinoline

Quinoline

SCHEMBL28779802

CCc1nc(C)cn1CC(O)COc1ccccc1.c1ccc2ncccc2c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGER Q15109 2/20 0.49
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 1/20 0.43
TSHR P16473 2/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAPT P10636 4/20 0.42
LMNA P02545 3/20 0.42
MAPK1 P28482 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
GAA P10253 1/20 0.42
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258463 0.90 CYP1A2 (0.54) AGERCYP1A2CYP3A4CYP2C9CYP2C19
Quinoline SCHEMBL28189854 0.78 AGER (0.51) AGERCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL6377520 0.78 CYP1A2 (0.56) AGERCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL28429464 0.74 MEN1 (0.55) AGERCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL258791 0.69 MEN1 (0.76) AGERCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL16603995 0.67 AGER (1.00) AGERCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL28619302 0.66 MEN1 (0.56) AGERCYP1A2CYP3A4CYP2C9CYP2C19
Ethane SCHEMBL27196683 0.66 CYP1A2 (0.56) AGERCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL18821302 0.65 CYP1A2 (0.74) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL18821437 0.64 AGER (0.59) AGERCYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101553545-B Bonding method and adhesive resin composition HENKEL CORP 2012-07-18 CN disclosed
CN-101553545-A Bonding method and adhesive resin composition HENKEL CORP (US) 2009-10-07 CN disclosed