SCHEMBL28782

SCHEMBL28782

O=C1c2ccccc2C(=O)c2occc21

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.76
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CDC25B P30305 1/20 0.55
NQO1 P15559 1/20 0.47
POR P16435 1/20 0.47
MAPT P10636 3/20 0.46
HTT P42858 3/20 0.46
APAF1 O14727 3/20 0.46
MAPK1 P28482 3/20 0.46
POLB P06746 2/20 0.46
TDP2 O95551 2/20 0.46
NPC1 O15118 2/20 0.46
MAOA P21397 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CES2 O00748 1/20 0.46
TERT O14746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364602 1.00 PTPRC (0.76) PTPRCMEN1KMT2ACDC25BNQO1
SCHEMBL9674258 0.91 PTPRC (0.91) PTPRCMEN1KMT2ACDC25BNQO1
SCHEMBL9672807 0.91 PTPRC (0.69) PTPRCMEN1KMT2ACDC25BNQO1
SCHEMBL16162323 0.88 PTPRC (0.62) PTPRCMEN1KMT2ACDC25BNQO1
SCHEMBL3273316 0.86 PTPRC (1.00) PTPRCMEN1KMT2ACDC25BNQO1
SCHEMBL12179511 0.84 PTPRC (0.60) PTPRCMEN1KMT2ACDC25BNQO1
SCHEMBL18384497 0.77 MAOA (0.58) PTPRCCDC25BNQO1PORMAPT
SCHEMBL16167323 0.77 NQO1 (0.47) PTPRCNQO1PORMAPK1NPC1
SCHEMBL28046 0.77 S100A4 (0.53) PTPRCNQO1PORMAPK1NPC1
SCHEMBL867205 0.75 MAOA (0.66) PTPRCMEN1KMT2ACDC25BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025058297-A1 COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING STAT3 INHIBITOR AND NICLOSAMIDE 국립암센터 2025-03-20 WO claimed
EP-2547334-B1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS 1GLOBE BIOMEDICAL CO LTD (CN) 2017-11-15 EP claimed
EP-2983790-A2 METHODS FOR TREATING CANCER Boston Biomedical, Inc. (US) 2016-02-17 EP claimed
WO-2014169078-A2 METHODS FOR TREATING CANCER BOSTON BIOMEDICAL, INC. (US) 2014-10-16 WO claimed
EP-2547334-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS Boston Biomedical, Inc. (US) 2013-01-23 EP claimed
EP-2547205-A1 NOVEL METHODS FOR TARGETING CANCER STEM CELLS Boston Biomedical, Inc. (US) 2013-01-23 EP claimed
WO-2011116399-A1 NOVEL METHODS FOR TARGETING CANCER STEM CELLS BOSTON BIOMEDICAL, INC. (US) 2011-09-22 WO claimed
WO-2011116398-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS BOSTON BIOMEDICAL, INC. (US) 2011-09-22 WO claimed
EP-1134216-B1 ANTI-DRUG RESISTANT STRAIN AGENTS AND ANTICHLAMYDIA AGENTS JAPAN SCIENCE & TECH CORP (JP) 2004-05-06 EP claimed
JP-9090652-A None JP disclosed
WO-2025058297-A1 COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING STAT3 INHIBITOR AND NICLOSAMIDE 국립암센터 2025-03-20 WO disclosed
EP-2547205-B1 NOVEL METHODS FOR TARGETING CANCER STEM CELLS 1GLOBE BIOMEDICAL CO LTD (CN) 2024-03-20 EP disclosed
CN-107375260-B Novel compounds and compositions for targeting cancer stem cells 北京强新生物科技有限公司 2023-10-24 CN disclosed
CN-113491690-B Use of 2-acetylnaphtho [2,3-b ] furan-4, 9-dione for treating cancer 北京强新生物科技有限公司 2023-03-14 CN disclosed
US-6337346-B1 BENZODITHIOPHENE DERIVATIVES UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2002-01-08 US disclosed
EP-1134216-A1 ANTI-DRUG RESISTANT STRAIN AGENTS AND ANTICHLAMYDIA AGENTS Japan Science and Technology Corporation (JP) 2001-09-19 EP disclosed
EP-1093456-A2 NAPHTHO- AND DIHYDROBENZO-THIOPHENE DERIVATIVES AS CYTOTOXIC ANTITUMOR AGENTS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2001-04-25 EP disclosed
WO-1999062909-A9 NAPHTHO- AND DIHYDROBENZO-THIOPHENE DERIVATIVES AS CYTOTOXIC ANTITUMOR AGENTS UNIV NORTH CAROLINA (US) 2000-04-27 WO disclosed
WO-1999062909-A2 NAPHTHO- AND DIHYDROBENZO-THIOPHENE DERIVATIVES AS CYTOTOXIC ANTITUMOR AGENTS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-12-09 WO disclosed
JP-H0990652-A ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITA IND CO LTD 1997-04-04 JP disclosed