Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1602886 | 0.86 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1602867 | 0.86 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL16554654 | 0.84 | SCD (0.57) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL12416497 | 0.84 | ALDH1A1 (0.58) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL24310716 | 0.84 | ALDH1A1 (0.68) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1257597 | 0.84 | ALDH1A1 (0.76) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13543686 | 0.82 | HSP90AA1 (0.56) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1602722 | 0.80 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1602861 | 0.80 | MARK4 (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2511099 | 0.77 | L3MBTL1 (0.56) | MEN1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511812-A | Pyrazole derivatives as cytochrome P450 inhibitors | PFIZER PROD INC (US) | 2009-08-19 | — | — | CN | disclosed |