Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894639 | 0.89 | KDM4E (0.55) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL27774057 | 0.86 | KDM4E (0.60) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL12330444 | 0.85 | KDM4E (0.55) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL27774171 | 0.85 | GABRA1 (0.57) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL28782276 | 0.85 | PYGL (0.62) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL2445804 | 0.83 | KDM4E (0.55) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2448160 | 0.83 | KDM4E (0.54) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2444412 | 0.83 | KDM4E (0.54) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL7845700 | 0.80 | NHERF1 (0.61) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL2479663 | 0.78 | KDM4E (0.68) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101624371-A | 4-carbostyril and 4H-1,4-benzothiazine derivatives and preparation method and application thereof | UNIV CHINA PHARMA | 2010-01-13 | — | — | CN | disclosed |