SCHEMBL2878248

SCHEMBL2878248

C=C(C)C(=O)OC(C)CC[SiH](OC)OC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22151015 0.90 TSHR (0.37) TSHRALDH1A1
SCHEMBL4222812 0.84 ALDH1A1 (0.39) TSHRALDH1A1THRB
SCHEMBL2878665 0.83 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL4005979 0.82 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL10958863 0.82 TSHR (0.44) TSHR
SCHEMBL2540758 0.81 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL28521905 0.80 ALDH1A1 (0.35) TSHRALDH1A1THRB
SCHEMBL977530 0.77 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL3411386 0.77 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL21641680 0.76 TSHR (0.35) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN claimed
US-8257805-B2 Insulated glass unit possessing room temperature-curable siloxane-containing composition of reduced gas permeability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-09-04 US claimed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP disclosed
EP-3310793-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-06-09 EP disclosed
CN-109195999-B Curable composition for photoimprint and pattern forming method using same DIC株式会社 2021-04-16 CN disclosed
CN-107743493-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-10-30 CN disclosed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN disclosed
US-10273254-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-30 US disclosed
US-10246473-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-02 US disclosed
EP-2143708-A1 OLIGOANILINE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-01-13 EP disclosed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN disclosed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN disclosed
EP-1234830-B1 Method of preparing an organosilicon compound containing a methacryloxy functional group DOW CORNING TORAY SILICONE (JP) 2005-01-19 EP disclosed
US-6448427-B1 REACTING AN ALKALI-METAL SALT OF (METH)ACRYLIC ACID WITH A HALOGEN SUBSTITUTED ORGANOSILICON COMPOUND IN THE PRESENCE OF A TERTIARY AMINE DIAZABICYCLO DERIVATIVE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-09-10 US disclosed
EP-1234830-A2 Method of preparing an organosilicon compound containing a methacryloxy functional group Dow Corning Toray Silicone Co., Ltd. (JP) 2002-08-28 EP disclosed
US-20020115878-A1 METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP DOW TORAY CO., LTD. (JP) 2002-08-22 US disclosed
US-5916963-A ACRYLIC ESTERS WITH SILICON GROUPS TOYO INK MANUFACTURING CO., LTD. (JP) 1999-06-29 US disclosed