SCHEMBL2878665

SCHEMBL2878665

C=C(C)C(=O)OC(C)CC[SiH](OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4222599 0.85 THRB (0.36) TSHRTHRBALDH1A1
SCHEMBL4196284 0.83 TSHR (0.39) TSHRTHRBALDH1A1
SCHEMBL2878248 0.83 TSHR (0.39) TSHRTHRBALDH1A1
SCHEMBL10965281 0.83 TSHR (0.41) TSHRALDH1A1
SCHEMBL2540758 0.78 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL5605423 0.77 TSHR (0.37) TSHR
SCHEMBL437295 0.77 TSHR (0.45) TSHRTHRBALDH1A1
SCHEMBL15536571 0.75 TSHR (0.40) TSHRTHRB
SCHEMBL14394272 0.75 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL22151015 0.74 TSHR (0.37) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
US-20020127330-A1 Organic-inorganic hybrid polymer and method of making same JIN DAN L (US) 2002-09-12 US claimed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US claimed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP claimed
EP-2143708-A1 OLIGOANILINE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-01-13 EP disclosed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN disclosed
EP-1664399-A4 SUPERABSORBENT CELLULOSIC FIBER AND METHOD OF MAKING SAME RAYONIER PROD & FNCL SERV CO (US) 2007-08-22 EP disclosed
EP-1664399-A2 SUPERABSORBENT CELLULOSIC FIBER AND METHOD OF MAKING SAME Rayonier Products and Financial Services Company (US) 2006-06-07 EP disclosed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN disclosed
US-20050085150-A1 Superabsorbent cellulosic fiber and method of making same RAYONIER ADVANCED MATERIALS INC. 2005-04-21 US disclosed
US-6844066-B2 Superabsorbent cellulosic fiber and method of making same RAYONIER PRODUCTS AND FINANCIAL SERVICES COMPANY (US) 2005-01-18 US disclosed
WO-2004103412-A2 SUPERABSORBENT CELLULOSIC FIBER AND METHOD OF MAKING SAME RAYONIER PRODUCTS AND FINANCIAL SERVICES COMPANY (US) 2004-12-02 WO disclosed
US-20040234760-A1 SUPERABSORBENT CELLULOSIC FIBER AND METHOD OF MAKING SAME RAYONIER PRODUCTS AND FINANCIAL SERVICES COMPANY 2004-11-25 US disclosed
US-6607590-B2 Clear protective thin film NANOFILM, LTD. 2003-08-19 US disclosed
US-6451420-B1 ORGANIC POLYMER AND SILICA MOLECULES CHEMICALLY BONDED TOGETHER BY COVALENT BONDS, POLYMERIZED PRODUCT OF OLIGOMERS FROM HYDROLYSIS OF TETRAALKYL SILICATE, EPOXYALKYLALKOXY SILANES, ACRYLOXYALKYLALKOXY;LENSES NANOFILM, LTD. 2002-09-17 US disclosed
US-20020127330-A1 Organic-inorganic hybrid polymer and method of making same JIN DAN L (US) 2002-09-12 US disclosed
US-20010036554-A1 Organic-incorganic hybrid polymer and method of making same NANOFILM LTD 2001-11-01 US disclosed
EP-1136520-A2 Organic- inorganic hybrid polymer and method of making the same nanoFILM, Ltd. (US) 2001-09-26 EP disclosed
US-5916963-A ACRYLIC ESTERS WITH SILICON GROUPS TOYO INK MANUFACTURING CO., LTD. (JP) 1999-06-29 US disclosed